2025 JPJC H2Bio PE P3 (QP)

9744 / 03 [Turn over NAME : CLASS : JURONG PIONEER JUNIOR COLLEGE JC2 Preliminary Examination 2025 BIOLOGY Higher 2 9744/03 15 September 2025 Paper 3 Long Structured and Free-response Questions 2 hours Additional Materials: Answer Booklet READ THESE INSTRUCTIONS FIRST Write your class and name in the spaces at the top of this page. Write in dark blue or black pen. You may use an HB pencil for any diagrams or graphs. Do not use staples, paper clips, glue or correction fluid. Section A Answer all questions in the spaces provided on the Question Paper. Section B Answer any one question on the separate Answer Booklet provided. The use of an approved scientific calculator is expected, where appropriate. You may lose marks if you do not show your working or if you do not use appropriate units. The number of marks is given in brackets [ ] at the end of each question or part question. For Examiner’s Use 1 2 3 Section B Total This document consists of 17 printed pages and 3 blank pages.

2 JPJC/JC2 H2 Biology/PE/2025 Section A Answer all questions. 1 Following a body injury, bone marrow stem cells migrate to the site of damage, where they undergo cell differentiation to replace damaged cells. In eukaryotes, cell growth and division are tightly regulated processes to ensure proper repair. Cells will only pass specific checkpoints in the cell cycle if certain conditions are met, one of which is the presence of growth factors. Fig. 1.1 shows how this differentiation occurs. Fig. 1.1 (a) (i) Outline how SCFR is produced and transported to the cell surface. ................................ ................................ ................................ ........................ ................................ ................................ ................................ ........................ ................................ ................................ ................................ ........................ ................................ ................................ ................................ ........................ ................................ ................................ ................................ ........................ ................................ ................................ ................................ ........................ ................................ ................................ ................................ ........................ ................................ ................................ ................................ ........................ ................................ ................................ ................................ ................... [4] (ii) Suggest how SCFR is destroyed by a lysosome. ................................ ................................ ................................ ...