2025 VJC H2 Biology Prelim P2

1 VICTORIA JUNIOR COLLEGE JC 2 PRELIMINARY EXAMINATION 2025 HIGHER 2 NAME : ……………………………………………………….………………. CT CLASS: ………………...……… BIOLOGY Paper 2 Structured Questions 9744 / 02 16/09/2025 2 hour Candidates answer on the Question Paper. No Additional Materials are required. READ THESE INSTRUCTIONS FIRST Write your name and CT class in the spaces at the top of this page. Write in dark blue or black pen. You may use an HB pencil for any diagrams or graphs. Do not use staples, paper clips, glue or correction fluid. Answer all questions in the spaces provided on the Question Paper. Use of an approved scientific calculator is expected, where appropriate. You may lose marks if you do not show your working or if you do not use appropriate units. The number of marks is given in bracket [ ] at the end of each question or part question. Question Marks 1 2 3 4 5 6 7 8 9 10 11 Total This document consists of 28 printed pages. [Turn over]

2 Answer all questions. 1 In most cell types, ribosomes are the most abundant organelles by number. They are present in both prokaryotic and eukaryotic cells, although their sizes and structures differ. (a) (i) State one structural feature of ribosomes that is common to both prokaryot ic and eukaryotic cells. …………………………………………………………………………………………………... ……………………………………………………………………………………………..… [1] (ii) Suggest how the difference in ribosome size between prokaryotic and eukaryotic cells can be exploited in medicine. …………………………………………………………………………………………………... …………………………………………………………………………………………………... …………………………………………………………………………………………………... ……………………………………………………………………………………………..… [2]

3 (b) Unlike prokaryotic and eukaryotic cells, viruses such as SARS -CoV-2 lack ribosomes entirely. Fig. 1.1 shows the structure of the SARS-CoV-2. Fig. 1.1 With reference to the information provided, (i) explain how the structural features of SARS-CoV-2 show that it does not fully conform to the cell theory. …………………………………………………………………………………………………... …………………………………………………………………………………………………... …………………………………………………………………………………………………... ……………………………………………………………………………………………..… [2] (ii) compare the genetic material between SARS-CoV-2 and prokaryotic cells. …………………………………………………………………………………………………... …………………………………………………………………………………………………... …………………………………………………………………………………………………... …………………………………………………………………………………………………... …………………………………………………………………………………………………... ……………………………………………………………………………………………..… [3] [Total: 8]

4 2 Proteins are large macromolecules that comprise one or more long chains of amino acid residues. A linear chain of amino acid residues is known as a polypeptide. A polypeptide is formed by ribosomes in a process called translation, in which amin