2024 TMJC Prelim H2 Bio Paper 1 (A)

1 CANDIDATE NAME CIVICS GROUP H2 BIOLOGY 9744/01 Paper 1 Multiple Choice Questions 19 September 2024 1 hour Additional material: Multiple Choice Answer Sheet ANSWERS WITH EXPLANATION QUESTION ANSWER QUESTION ANSWER 1 B 16 A 2 C 17 B 3 C 18 C 4 D 19 A 5 A 20 D 6 C 21 D 7 A 22 C 8 D 23 C 9 D 24 B 10 A 25 C 11 B 26 D 12 B 27 D 13 D 28 D 14 C 29 B 15 A 30 C ________________________________________________________________________________ This document consists of 24 printed pages. TAMPINES MERIDIAN JUNIOR COLLEGE JC2 PRELIMINARY EXAMINATION

2 Tampines Meridian Junior College 2024 JC2 Preliminary Examination H2 Biology [Cell 1/2, KU-1] 1. Six organelles found in eukaryotic cells are shown. They are not drawn to scale. Which organelles are involved in the synthesis and secretion of a glycoprotein? A. 1, 2, 3 and 4 B. 1, 2, 4 and 6 C. 2, 3 and 5 D. 3, 4, 5 and 6 Explanation • 1 = nucleus, 2 = mitochondria, 3 = centrioles, 4 = RER, 5 = chloroplast, 6 = Golgi apparatus • Nucleus carries gene coding for the protein. It is also where transcription takes place. • RER is where translation takes place. The protein enters the ER lumen where folding and glycosylation occurs. • Golgi further modifies the glycoprotein and packages them into a secretory vesicles. • Mitochondria synthesizes ATP needed for protein synthesis and movement of vesicles along microtubules. [Cell 2/2, KU-1] 2. What is present in all viruses, prokaryotes and eukaryotes? A. thymine B. deoxyribose C. adenine D. phospholipid Explanation • Thymine is present in DNA. Some viruses are RNA viruses (hence no thymine). • Deoxyribose is present in DNA. Some viruses are RNA viruses (hence no DNA). • Some viruses are non-enveloped, hence no phospholipids.

3 Tampines Meridian Junior College 2024 JC2 Preliminary Examination H2 Biology [BioMol 1/2, KU-1] 3. The diagrams show the structures of two amino acids, aspartic acid and lysine. Which groups form the bonds that maintain the primary, secondary and tertiary structures of proteins? primary structure secondary structure tertiary structure A. 2, 6 1, 3, 4, 5 1, 3, 4, 5 B. 1, 3, 4, 5 2, 6 2, 6 C. 1, 3, 4, 5 1, 3, 4, 5 2, 6 D. 2, 6 2, 6 1, 3, 4, 5 Explanation: • 1 and 4 are the amino group, and 3 and 5 are the carboxylic acid group. They form peptide bonds that link amino acids together to form the primary structure (sequence of amino acids). • The C=O group and ─NH groups of the peptide bond regions are needed to form hydrogen bonds in alpha helices and beta pleated sheets. • The R-groups, which are CH2COOH in aspartic acid and CH2CH2CH2CH2NH2 in lysine forms bonds with other R-groups to maintain the globular (tertiary) structu