RVHS 8. Transcription and Translation

River Valley High School 1 2025 JC1 H2 Biology Lecture Topic 8: Transcription and Translation River Valley High School 2025 JC1 H2 Biology Lecture Topic 8: The Structure of Nucleic Acids and Gene Expression – Transcription and Translation Name: ( ) Class: 25J___ Date: References Title Author Biology (9th edition) Campbell and Reece Molecular Biology of the Cell (5th edition) Alberts, Johnson, Lewis, Raff, Roberts and Walter Biological Science 1 and 2 (3rd Edition) Taylor, Green and Stout Molecular Biology of the Cell (5th edition) Alberts, Johnson, Lewis, Raff, Roberts and Walter Principles of Genetics (3rd edition) Snustad and Simmons Molecular Cell Biology (6th edition) Lodish, Berk, Kaiser, Krieger, Scott, Bretscher, Ploegh and Matsudaira Advanced Biology: Principles and Applications (2nd edition) Clegg and Mackean Websites URL Description http://learn.genetics.utah.edu/content/basics/transcribe/ Interactive website on protein synthesis https://highered.mheducation.com/sites/9834092339/stu dent_view0/chapter15/protein_synthesis.html Watch the video linked on page 10 and complete the Chapter 15 quiz to reinforce your understanding of the concepts. http://www.dnaftb.org/ Plenty of animations / video clips for DNA- related mechanisms. Refer mainly to “Molecules of Genetics” tab

River Valley High School 2 2025 JC1 H2 Biology Lecture Topic 8: Transcription and Translation H2 Biology Syllabus 9477 (2025) Candidates should be able to use the knowledge gained in the following section(s) in new situations or to solve related problems. Related Topics Content DNA Replication DNA structure and function Learning Outcomes 2A. The Structure of Nucleic Acids and Gene Expression a. describe the structure and roles of DNA and RNA (tRNA, rRNA and mRNA) c. Describe how the information on DNA is used to synthesise polypeptides (description of the processes of transcription, formation of mRNA from pre -mRNA in eukaryotes and translation is required) Lecture Outline I. Central Dogma of Molecular Biology II. Transcription (Synthesis of RNA) A. Structure of RNA B. Overview of Transcription C. Process of Transcription D. Features of mRNA III. Translation (Synthesis of Polypeptides) A. Overview of Translation B. Features of the Genetic code C. Structure-Function Relationships of tRNA D. Structure-Function Relationships of ribosome E. Process of Translation F. From Polypeptide to Functional Protein

River Valley High School 3 2025 JC1 H2 Biology Lecture Topic 8: Transcription and Translation I. Central Dogma of Molecular Biology ⬧ Central dogma of molecular biology – the flow of genetic information in all cells, from DNA to DNA and from DNA to RNA to protein. ⬧ Genetic information is transferred from DNA to DNA during its transmission from generation to generation. ⬧ Genetic information is transferred from DNA to RNA and then to protein during its p