RVHS 7. DNA Replication

River Valley High School 1 2025 JC1 H2 Biology Lecture Topic 7: DNA Replication River Valley High School 2025 JC1 H2 Biology Lecture Topic 7: The Structure of Nucleic Acids and Gene Expression – DNA Replication Name: ( ) Class: 25J____ Date: References Title Author Biology (9th edition) Campbell and Reece Biological Science 1 and 2 (3rd Edition) Taylor, Green and Stout Molecular Biology of the Cell (5th edition) Alberts, Johnson, Lewis, Raff, Roberts and Walter Principles of Genetics (3rd edition) Snustad and Simmons Molecular Cell Biology (6th edition) Lodish, Berk, Kaiser, Krieger, Scott, Bretscher, Ploegh and Matsudaira H2 Biology Syllabus 9477 (2025) Candidates should be able to use the knowledge gained in the following section(s) in new situations or to solve related problems. Related Core Topics Content Transcription and Translation Central Dogma – DNA to RNA, RNA to protein Learning Outcomes 2A: The Structure of Nucleic Acids and Gene Expression a. describe the structure and roles of DNA and RNA (tRNA, rRNA and mRNA) (knowledge of the structure and roles of mitochondrial DNA and chloroplast DNA is not required) b. describe the process of DNA replication and how the end replication problem arises Lecture Outline I. Role of DNA as the Hereditary Material II. Structure of DNA A. Building Blocks of Nucleic Acids B. Physical Structure of DNA III. Replication of DNA A. DNA Strands as Templates for Replication B. Mechanism of DNA replication C. DNA Repair and Maintenance

River Valley High School 2 2025 JC1 H2 Biology Lecture Topic 7: DNA Replication Websites URL Description http://learn.genetics.utah.edu/content/basics/ Website on the basics of genetics with videos and interactive activties https://highered.mheducation.com/sites/98340923 39/student_view0/chapter14/dna_replication.html Animations on DNA replication (Chapter 14)* Chapter quiz to help reinforce concepts *Note: you would need to use a laptop/desktop and download a chrome extension (e.g. “Flash Player for Chrome”) to view the tutorial. http://www.dnaftb.org/ Animations** and video clips for DNA-related content (under Molecules of Genetics). **Note that the animations will take some time to load. https://www.dnalc.org/resources/nobel/crick_wats on_wilkins.html Animations which illustrate how the DNA structure was decoded

River Valley High School 3 2025 JC1 H2 Biology Lecture Topic 7: DNA Replication I. Role of DNA as the Hereditary Material Introduction ⬧ Life depends on the ability of cells to store, retrieve and translate the genetic instructions required to make and maintain a living organism. ⬧ This hereditary information is passed on from a cell to its daughter cells at somatic cell division, and from one generation of an organism to the next through the organism’s reproducti ve cells. ⬧ These instructions are stored within every living cell as its