RVHS 9. Organisation of Genomes - Eukaryotes 9477

River Valley High School 1 2025 JC1 H2 Biology Lecture Topic 9: Organisation of Genomes - Eukaryotes River Valley High School 2025 JC1 H2 Biology Lecture Topic 9: Organisation of Genomes - Eukaryotes Name: ( ) Class: 25J____ Date: References Title Authors Biology (9th Edition) Campbell and Reece Biology: An Australian Focus (3rd Edition) Knox, Ladiges, Evans and Saint Molecular Cell Biology (6th Edition) Lodish, Berk, Kaiser, Krieger, Scott, Bretscher, Ploegh and Matsudaira Molecular Biology of the Cell (5th Edition) Alberts, Johnson, Lewis, Raff, Roberts and Walter Principles of Genetics (3rd Edition) Snustad and Simmons H2 Biology Syllabus 9477 (2025) Candidates should be able to use the knowledge gained in the following section(s) in new situations or to solve related problems. Related Topics Content Control of Gene Expression - Eukaryotes Organisation of Genomes - Prokaryotes Control of eukaryotic gene expression Prokaryotic genome Learning Outcomes 2B. Organisation of Genomes a. Describe the structure and organisation of viral, prokaryotic and eukaryotic genomes (including DNA/RNA, single-/double-stranded, number of nucleotides, packing of DNA, linearity/circularity and presence/absence of introns). e. Describe the structure and function of non -coding DNA in eukaryotes (i.e. portions that do not encode protein or RNA, including introns, cen tromeres, telomeres, promoters, enhancers a nd silencers) (knowledge of transposons, satellite DNA, pseudo -genes and duplication of segments is not required). Lecture Outline I. Structure and Organisation of Eukaryotic Chromosomes A. Relating Structure of Eukaryotic Chromosomes to Cell Cycle B. Packing of DNA in Eukaryotic Chromosomes C. Organisation of DNA in Eukaryotic Chromosomes i. Coding and Non-coding DNA ii. Relating Structure of Centromere to its Role iii. Relating Structure of Telomere to its Role D. Comparing the Structure/Organisation of Prokaryotic & Eukaryotic Chromosomes

River Valley High School 2 2025 JC1 H2 Biology Lecture Topic 9: Organisation of Genomes - Eukaryotes Websites URL Description https://www.dnalc.org/resources/3d/08-how- dna-is-packaged-advanced.html packing of DNA in eukaryotic chromosome. https://highered.mheducation.com/sites/983409 2339/student_view0/chapter14/telomerase_func tion.html description of telomerase action. *Note: you would need to use a laptop/desktop and download a chrome extension (e.g. “Flash Player for Chrome”) to view the tutorial.

River Valley High School 3 2025 JC1 H2 Biology Lecture Topic 9: Organisation of Genomes - Eukaryotes I. STRUCTURE AND ORGANISATION OF EUKARYOTIC CHROMOSOMES The genomes of most eukaryotes are larger and more complex than those of prokaryotes. In this chapter, we shall consider the characteristics of eukaryotic genome1 (in particular, the eukaryotic nuclear genome), i.e. the features of genes and the other DNA sequences that comprise t